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Index > Protein center > Proc(Gene name) > Mouse
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  • Proc (Gene name),
  • Vitamin K-dependent protein C (Protein name ),  PROC_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Proc;
    Protein name:
    Vitamin K-dependent protein C;
    Alternative:
    Autoprothrombin IIA;Anticoagulant protein C;Blood coagulation factor XIV;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Synthesized as a single chain precursor, which is cleaved into a light chain and a heavy chain held together by a disulfide bond. The enzyme is then activated by thrombin, which cleaves a tetradecapeptide from the amino end of the heavy chain; this reaction, which occurs at the surface of endothelial cells, is strongly promoted by thrombomodulin.
    Function:
    Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    460
    Sequence:
    50:
    MWQFRVFLLL | MSTWGISSIP | AHPDPVFSSS | EHAHQVLRVR | RANSFLEEMR | 
    100:
    PGSLERECME | EICDFEEAQE | IFQNVEDTLA | FWIKYFDGDQ | CSAPPLDHQC | 
    150:
    DSPCCGHGTC | IDGIGSFSCS | CDKGWEGKFC | QQELRFQDCR | VNNGGCLHYC | 
    200:
    LEESNGRRCA | CAPGYELADD | HMRCKSTVNF | PCGKLGRWIE | KKRKILKRDT | 
    250:
    DLEDELEPDP | RIVNGTLTKQ | GDSPWQAILL | DSKKKLACGG | VLIHTSWVLT | 
    300:
    AAHCVEGTKK | LTVRLGEYDL | RRRDHWELDL | DIKEILVHPN | YTRSSSDNDI | 
    350:
    ALLRLAQPAT | LSKTIVPICL | PNNGLAQELT | QAGQETVVTG | WGYQSDRIKD | 
    400:
    GRRNRTFILT | FIRIPLVARN | ECVEVMKNVV | SENMLCAGII | GDTRDACDGD | 
    450:
    SGGPMVVFFR | GTWFLVGLVS | WGEGCGHTNN | YGIYTKVGSY | LKWIHSYIGE | 
    460:
    KGVSLKSQKL | 
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    KEGG:
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Vitamin K-dependent protein C
    Cat.:
    E0734h
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    ELISA Kit for Mouse Vitamin K-dependent protein C
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    ELISA Kit for Mouse Vitamin K-dependent protein C
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    E0734r
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    ELISA Kit for Mouse Vitamin K-dependent protein C
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    E0734p
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    ELISA Kit for Mouse Vitamin K-dependent protein C
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    E0734d
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    96T
    ELISA Kit for Mouse Vitamin K-dependent protein C
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    E0734m
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    ELISA Kit for Mouse Vitamin K-dependent protein C
    Cat.:
    E0734b
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    Packing:
    96T
    CLIA Kit for Mouse Vitamin K-dependent protein C
    Cat.:
    U0734m
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    96T
    CLIA Kit for Mouse Vitamin K-dependent protein C
    Cat.:
    U0734p
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Vitamin K-dependent protein C
    Cat.:
    U0734r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Vitamin K-dependent protein C
    Cat.:
    U0734h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Vitamin K-dependent protein C
    Cat.:
    U0734d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Vitamin K-dependent protein C
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Vitamin K-dependent protein C
    Cat.:
    U0734b
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse Vitamin K-dependent protein C
    Polyclonal Antibody for Mouse Vitamin K-dependent protein C
    Cat.:
    P0734Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Vitamin K-dependent protein C
    Polyclonal Antibody for Mouse Vitamin K-dependent protein C
    Cat.:
    P0734Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Vitamin K-dependent protein C
    Cat.:
    P0734Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Vitamin K-dependent protein C
    Polyclonal Antibody for Mouse Vitamin K-dependent protein C
    Monoclonal Antibody for Mouse Vitamin K-dependent protein C
    Monoclonal Antibody for Mouse Vitamin K-dependent protein C
    Monoclonal Antibody for Mouse Vitamin K-dependent protein C
    Monoclonal Antibody for Mouse Vitamin K-dependent protein C
    Monoclonal Antibody for Mouse Vitamin K-dependent protein C
    Monoclonal Antibody for Mouse Vitamin K-dependent protein C
    Monoclonal Antibody for Mouse Vitamin K-dependent protein C
    Protein for Mouse Vitamin K-dependent protein C
    Protein for Mouse Vitamin K-dependent protein C
    Protein for Mouse Vitamin K-dependent protein C
    Protein for Mouse Vitamin K-dependent protein C
    Protein for Mouse Vitamin K-dependent protein C
    Protein for Mouse Vitamin K-dependent protein C
    Protein for Mouse Vitamin K-dependent protein C

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    References
    1. 1.
      "Isolation and characterization of a mouse protein C cDNA."
      Tada N. , Sato M. , Tsujimura A. , Iwase R. , Hashimoto-Gotoh T.
      J. Biochem.111:491-495(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: BALB/c.
      tissue: Liver.
    2. 2.
      "Nucleotide structure and characterization of the murine gene encoding anticoagulant protein C."
      Jalbert L.R. , Rosen E.D. , Lissens A. , Carmeliet P. , Collen D. , Castellino F.J.
      Thromb. Haemost.79:310-316(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: 129/SvJ.
    3. 3.
      "Complete sequence of UC72A01."
      Korf I.
      Submitted (2000-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
      strain: C57BL/6.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Liver.
    5. 5.
      "A comparative study of partial primary structures of the catalytic region of mammalian protein C."
      Murakawa M. , Okamura T. , Kamura T. , Kuroiwa M. , Harada M. , Niho Y.
      Br. J. Haematol.86:590-600(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 274-433
      strain: BALB/c.
    6. 6.
      "Proteome-wide characterization of N-glycosylation events by diagonal chromatography."
      Ghesquiere B. , Van Damme J. , Martens L. , Vandekerckhove J. , Gevaert K.
      J. Proteome Res.5:2438-2447(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-214
      strain: C57BL/6.
      tissue: Plasma.
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